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Mouse IL-18 Sandwich Immunoassay
| Recommended Concentration | Sample | |
|---|---|---|
| ELISA Capture | 1-4 μg/mL | Rabbit anti-Mouse IL-18 mAb (Cat. No. RMK0675) |
| ELISA Detection | 0.0025-0.01 μg/mL | Rabbit anti-Mouse IL-18 mAb (Cat. No. RMK0676) |
| Standard | 15.63-1000 pg/mL | Recombinant Mouse IL-18 Protein (Cat. No. RP02521) |
Enables cytokine activity. Involved in lipid homeostasis; positive regulation of cell differentiation; and positive regulation of cold-induced thermogenesis. Acts upstream of or within several processes, including interleukin-18-mediated signaling pathway; positive regulation of NIK/NF-kappaB signaling; and positive regulation of interferon-gamma production. Located in extracellular space. Is expressed in several structures, including back skin; dorsal aorta; gut; lymphatic system; and reproductive system. Used to study atopic dermatitis. Human ortholog(s) of this gene implicated in several diseases, including Kawasaki disease; allergic rhinitis; autoimmune disease (multiple); biliary atresia; and hepatitis B. Orthologous to human IL18 (interleukin 18).